Promethazine codeine syrup - An Overview
Promethazine codeine syrup - An Overview
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Promethazine HCl and Codeine Phosphate Oral Alternative should be employed with warning in individuals with impairment of hepatic functionality, and patients really should be monitored carefully for respiratory melancholy, sedation, and hypotension.
Anticholinergics – Concomitant utilization of other agents with anticholinergic Homes ought to be carried out with warning.
A likely deadly symptom elaborate at times referred to as Neuroleptic Malignant Syndrome (NMS) continues to be described in association with promethazine HCl on your own or together with antipsychotic medication.
Symptoms and signs or symptoms of overdosage with promethazine HCl range between gentle depression from the central nervous system and cardiovascular procedure to profound hypotension, respiratory despair, unconsciousness, and sudden Demise.
Preserve out of the access of children and pets. This medication could be abused. Keep it in a secure place to shield it from theft. Tend not to share it with anybody. It is only for you. Providing or making a gift of this medication is harmful and versus the law.
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A Health care Expert ought to be consulted before taking any drug, changing any diet program or commencing or discontinuing any class of treatment method.
Promethazine Carcinogenicity studies ended up performed with promethazine hydrochloride. Two-yr studies in F344/N rats and B6C3F1 mice had been executed to evaluate the carcinogenic opportunity of promethazine hydrochloride. No evidence of tumorigenicity was noticed in male and female rats at promethazine hydrochloride oral doses up to 33 mg/kg/day for 5 days/7 days (roughly similar to 10 occasions the MRHD over a mg/m2 basis).
Codeine is among the naturally happening phenanthrene alkaloids of opium derived from the opium poppy; it is assessed pharmacologically being a narcotic analgesic.
Animal reproduction scientific studies have not been conducted While using the drug mix-promethazine and codeine. It's not necessarily identified regardless of whether this drug blend may cause fetal damage when administered into a Expecting lady or can affect replica ability.
Promethazine hydrochloride wasn't mutagenic while in the in vitro bacterial reverse mutation assay or clastogenic inside the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
Codeine Codeine and its active metabolite, morphine, are current in human milk. There are revealed scientific tests and instances that have described extreme sedation, respiratory depression and Loss of life (in one toddler) in infants exposed to codeine by way of breast milk. Women of all ages who're ultra-swift metabolizers of codeine realize increased than anticipated serum levels of morphine, probably leading to larger amounts of morphine in breast milk that may Promethazine codeine syrup be perilous within their breastfed infants.
This drug may perhaps cause you to dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) could make you more dizzy or drowsy. Do not travel, use machinery, or do everything that desires alertness or very clear eyesight until eventually you can do it safely.
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